Shahjada Selim
Bangabandhu Sheikh Mujib Medical University, Bangladesh
Title: Dyslipidaemia as a risk factor for Erectile dysfunction in Type 2 diabetes mellitus patients
Biography
Biography: Shahjada Selim
Abstract
Objective: Studies have reported an inverse correlation between low levels of HDL cholesterol and increased risk of ED. To expand our knowledge on modifiable risk factors of ED within diabetic patients and dyslipidemia, we conducted a cross-sectional observational study.
Method: The study involved 813 males (20-69 years) with type-2 diabetes. Subjects were recruited from outpatient and inpatient department in Bangladesh from Bangladesh Institute of Research and Rehabilitation in Diabetes. Sexual function was evaluated with the International index of erectile function after translation into a Bengali version and validated under proper validation protocol.
Result: The mean cholesterol level of the sample was 184.5±41.5 mg/dl with 37% having levels higher than normal. Raised levels of HDL and LDL were found in 31% of subjects and elevated triglyceride levels were present in 57% of participants. The diabetic subjects with ED in the study were significantly older (p=0.000) and had suffered from diabetes for a longer duration of time (p=0.000). Independently abnormal levels of cholesterol (P=0.000), HDL (P=0.000), LDL (P=0.000) and triglyceride levels (P=0.000) all proved to be significant determinants of ED in the study population (table). Increased diabetes control was also found to be significantly associated with ED in the study.
Conclusion: Dyslipidemia was found to have the most significant risk associated with increased ED with the lipoproteins of lowered HDL and increased LDL levels demonstrating substantial influence of ED risk in diabetic patients.
