7th Indo Global Diabetes Summit and Medicare Expo
Madurai Kamaraj University
Title: Role of microRNAs in diabetic heart
Biography: Subbiah Ramasamy
Diabetes is one of the most common chronic disorders in the world population. Numerous and complex factors includingrnvarious genetic and physiological changes can lead to develop two types of diabetes: Type-1 diabetes (T1D) is due to selfdestructionrnof the insulin producing β-cells/Type-2 diabetes (T2D) is caused by defects in insulin production in the pancreas.rnBoth types of diabetes develop serious secondary complications, such as microvascular complications, oxidative stress, footrncomplications related to peripheral, neuropathy, peripheral vascular disease and cardiovascular disease. However, the majorrnmolecular mechanisms of pathogenesis of diabetic with cardiac complications remain obscure. With the recent discovery ofrnMicroRNAs (miRNAs), these small non-coding RNAs have been implicated as new players in the pathogenesis of diabetes andrndiabetes-associated cardiac complications. Significantly, the gene profiling techniques has been widely used as early diagnosticrnand prognostic biomarker especially in the area of diabetic cardiac complication research.