11^th Asia Pacific Diabetes Conference and Expo July 11-12, 2016 Brisbane, Australia

The global diabetes treatment market is undergoing significant transition driven by the advent of new analytical technologies and developments in diabetes treatment. There has been a drastic increase in the incidents of diabetes worldwide, owing to the rising level of lifestyles and obesity in global population. The diabetes treatment products include injectable diabetes drugs, oral drugs, insulin therapies, insulin pumps, insulin injection devices and blood glucose monitoring systems which eliminates the risk of reverse diabetes. According to the new report the world market for diabetes medications will reach $55.3bn in 2017. The anti-diabetic medicines industry generated $35.6bn in 2012, and its revenues will show strong growth to 2023. Monitoring glucose levels is critical for the management of diabetes and new and improved portable, less costly, easy-to-use, accurate and virtually painless blood glucose monitoring systems are now available to take control of the disease.

Diabetes has increasingly become a lifestyle-related disease as it afflicts young and old. As the number of patients grows across the globe, there has never been a stronger and more urgent need for novel therapeutic measures in clinical and preclinical evaluation, that arrest the growth of the disease. The diabetes market, consisting mainly of Type 1 and Type 2 diabetes, is large and growing significantly. The global market value for diabetes therapies and diagnostics has reached to $48.5 billion. The largest segment of the market, insulin products, is worth $20.8 billion in the recent times, including administration and diagnostic devices. Monitoring devices and other related equipment, the second-largest market is established with an investment of $13.5 billion in which was proposed for $11.3. The fastest-growing segment of oral diabetic complication of hypoglycemia drugs manufacturing funding is $14.13 in present scenario of diabetes market.

With the growing awareness and information regarding preventive measures for combating fatal disease like diabetes, consumers are opting for proper food along with medicines. One can improve the health in a big way by making small changes to the diet, while still enjoying the favorite foods and taking pleasure from the meals. A diabetes diet is simply a healthy eating plan that is high in nutrients, low in fat, and moderate in calories. Manufacturers are now keen towards Diabetes Nutrition on introducing new low calorie food products with sugar substitutes and less oil, in view of the increasing consumer interest toward healthy eating and help prevent diabetes and its concomitant risk factors.

Current Research in diabetes is focusing on developing Implantable insulin pumps which introduced Insulin pump therapy, disruption of fat metabolism, invasive and non-invasive glucose sensors, Artificial pancreas, New insulin delivery systems like inhaled, transdermal and implantable devices, Insulin Pens, Bariatric surgery and Conventional therapeutic approaches. Traditional approaches like Acupuncture and herbal medications are playing vital role in treatment of Diabetes and its related risk factors covering majorly obesity and Diabetes.

Diabetes is one of the most significant global health concerns of modern times. The causes of type 2 diabetes are multi-factorial and include both genetic and environmental elements that affect beta-cell function and tissue (muscle, liver, adipose tissue, and pancreas) insulin sensitivity. A number of factors have been suggested as possibly linking insulin resistance and beta-cell dysfunction in the pathogenesis of Type 2 Diabetes. A majority of individuals suffering from type 2 diabetes are obese, with central visceral adiposity. According to the International Diabetes Federation, diabetes statistics says that there are more than 317 million people have been diagnosed with diabetes, and an additional 187 million are living undiagnosed. The global revenue earned from drugs sales to treat Type 2 Diabetes was approximately $36.89 billion in 2012 that is rapidly increasing in incidence and prevalence across the globe predicated to elevate this figure to approximately $68.42 billion by 2017. Patients with this disease cannot use glucose properly for their body needs. Latest research on Diabetes has led to the better living of the diabetic patients. In addition to this, self-monitoring of Blood glucose levels, lifestyle modifications and health eating habits are crucial in combating the critical manifestations of this disease which may require proper diabetic nursing. This may also include considerable amount of time educating patients and families on proper dietary, exercise and lifestyle habits to keep symptoms under control.

Novel therapeutic targets available for diabetes includes Incretin based therapies, oral therapeutic agents like secretagogues, beta cell regeneration & proliferation and stem cell therapies.  Embryonic stem cell and fetal precursor cell transplantation therapies are the major stem cell therapies available for Diabetes. Apart from the above, various computational approaches in Diabetes management have been introduced recently with latest diabetes clinical trial going on which are playing an important role in identification of genes causing diabetes helping in Early Detection of Diabetes. These processes are also useful in studying the chemical etiologies of Diabetes uncovering various treatment prospects and model construction processes for survival prediction combating the complications of diabetes like Gestational Diabetes, Diabetes Myopathy, Diabetes cardiopathy and more.

Diabetes Mellitus is a dreadful disease and is found in all parts of the world, becoming a serious threat of mankind health. There are lots of chemical agents available to take control on the disease, but total recovery from diabetes is the question to the treatment. Alternative to these synthetic agents, natural cure by plants provides a potential source curing complications of hypoglycemia and reverse Diabetes are widely used in several traditional systems of medicine to prevent prediabetes. Other alternative therapies such as diabetic supplements, acupuncture, hydrotherapy, and yoga therapies are reported to have less likely side effects of conventional approaches for diabetes.

The concept of 'new technologies' for type 1 diabetes and new discovery and emerging therapies in type 2 diabetes has expanded in recent years at a rate that some might consider comparable to 'Moore’s Law', and the sheer number of new technologies entering into the type 1 diabetes marketplace is also growing at a remarkable rate. From the patient’s perspective, this is not only exciting but can lead to a sense of optimism. Technologies that today are growing commonplace (e.g. insulin pumps, rapid HbA1c monitoring, etc come under new therapeutic mechanisms of diabetes. Indeed, it could be argued that the major advances in type 1 diabetes care made within the last quarter of a century have come from technology rather than biology. At the same time, not all new technologies succeed (e.g. the Glucowatch), regardless of their purported promise. Both type 1 diabetes patients and their healthcare providers will soon see a series of further advanced medical technologies used in hospital and new technologies and novel therapies in diabetes treatment whose basis is tied to the notion of improving the lives of those with the disease.The concept of 'new technologies' for type 1 diabetes and new discovery and emerging therapies in type 2 diabetes has expanded in recent years at a rate that some might consider comparable to 'Moore’s Law', and the sheer number of new technologies entering into the type 1 diabetes marketplace is also growing at a remarkable rate. From the patient’s perspective, this is not only exciting but can lead to a sense of optimism. Technologies that today are growing commonplace (e.g. insulin pumps, rapid HbA1c monitoring, etc come under new therapeutic mechanisms of diabetes. Indeed, it could be argued that the major advances in type 1 diabetes care made within the last quarter of a century have come from technology rather than biology. At the same time, not all new technologies succeed (e.g. the Glucowatch), regardless of their purported promise. Both type 1 diabetes patients and their healthcare providers will soon see a series of further advanced medical technologies used in hospital and new technologies and novel therapies in diabetes treatment whose basis is tied to the notion of improving the lives of those with the disease.

Diabetes constitutes a major public health problem. Although substantial progress has been made in defining the genetics of metabolic syndrome risk for specific subtypes of diabetes (e.g., maturity-onset diabetes of the young), the majority of genetic risk of diabetes (for type 1 and type 2) remain unresolved. This review focuses on the current knowledge of the genetic basis of diabetes and its complications, specifically diabetic nephropathy (DN), recent advances in genetics of diabetes, diabetes in ethnic groups, genetic lifestyle interactions and understanding the genetics of Diabetes. Ultimately, identification of genes that contribute to risk (or protection) of diabetes and its complications will allow identification of patients who have diabetes and are at risk and targeted treatment/interventional strategies.