Bangaru Lalitha K
Research Scholar, Bharathiar University, Coimbatore
Title: Biochemical and statistical analysis on diabetic retinopathy in humans
Biography
Biography: Bangaru Lalitha K
Abstract
Diabetic retinopathy is the result of microvascular retinal changes. Hyperglycemia-induced intramural pericyte death and thickening of the basement membrane lead to incompetence of the vascular walls. These damages change the formation of the blood-retinal barrier and also make the retinal blood vessels become more permeable. As the disease progresses, severe nonproliferative diabetic retinopathy enters an advanced, or proliferative (PDR), stage when blood vessels proliferate (i.e. grow). The lack of oxygen in the retina causes fragile, new, blood vessels to grow along the retina and in the clear, gel-like vitreous humor that fills the inside of the eye. Without timely treatment, these new blood vessels can bleed, cloud vision, and destroy the retina. Fibrovascular proliferation can also cause fractional retinal detachment. The new blood vessels can also grow into the angle of the anterior chamber of the eye and cause Neovascular glaucoma. The primary focus of the current research work is to find out to identify the predominant blood group affected by Retinopathy diabetes using clinical and statistical tools. The outcome of the project work would be useful in the field of diabetic research studies.