
Emilio Herrera
Faculties of Pharmacy and Medicine
University San Pablo-CEU
Spain
Biography
Emilio Herrera is PhD from Complutense University (Madrid), Emeritus professor of Biochemistry and Molecular Biology at Faculties of Pharmacy and Medicine, University San Pablo-CEU in Madrid, Spain and Doctor Honoris causa in Medicine by Lund University (Sweden). He carried out his postdoctoral studies in Harvard University and Northwestern University Medical Schools. He has 282 peer-reviewed papers with IF (total IF by JCR-2009, 755.20) and 77 book chapters, having a h-index of 37 and has directed 49 PhD thesis.
Research Interest
Role of maternal lipids on neonatal body weight under healthy and gestational diabetic conditions
Biography
Dr. Collino was born in Italy, on 19th January 1973. Degree in Pharmaceutical Chemistry and Technology at the University of Turin, Faculty of Pharmacy, March 1998: summa cum laude. Ph. D. in “Pharmacology and Toxicology” at the University of Turin, 1998 – 2002. Visiting Scientist at The William Harvey Research Institute, Centre for Experimental Medicine, Nephrology & Critical Care, Barts and The London, Queen Mary\s School of Medicine and Dentistry, London (UK) in the years 2003-2004. Since 2002 Assistant Professor of Pharmacology, Faculty of Pharmacy, University of Turin. Member of the Italian Society of Pharmacology, the European Biomedical Research Association. , British Pharmacological Society, European Shock Society
Research Interest
His research activity is focused mainly on the investigation of innovative pharmacological strategies for metabolic disorders and the related cardiovascular complications
Biography
Sebastian studied clinical medicine at “Iuliu Hatieganu” Medical School, Cluj-Napoca, Romania and trained as a junior doctor in Nephrology and Dialysis before moving to USA where he obtained a PhD from the University of Nebraska-Lincoln in 2004.This was followed by postdoctoral training at Duke University Medical Center (North Carolina, USA) where he became interested in studying the connections between alternative splicing and cancer. Using fluorescent splicing reporters that recapitulate in vivo the alternative splicing of fibroblast growth factor 2 and are able to follow epithelial-mesenchymal transitions he discovered unusual plasticity in prostate cancer cells in animal models. This was further followed by studies of circulating tumour cells from patients showing that the same plasticity is associated with aggressive prostate and breast cancer behavior.Since moving to the University of Bristol in 2008 he continued to study alternative splicing in vivo, switching the focus towards the importance of VEGF splice isoforms in cancer as well as kidney diseases.
Research Interest
My main research interests include the study of alternative splicing in vivo, coordinated regulation of alternative splicing in physiology and disease as well as manipulation of splice isoforms choice for therapeutic goals. Alternative splicing is the main process that decides the diversity of proteins in our bodies. It is estimated that more than 90% of genes are alternatively spliced in humans and therefore this process affects all cellular properties. The function of the majority of splicing isoforms is not characterized yet. Numerous splicing isoforms have been associated with disease progression in recent years and there is much interest in understanding their contribution to pathogenesis and how this can be reversed.